From points north via I-95: New York, New Jersey, Pennsylvania, Delaware, and elsewhere

Follow I-95 South toward Baltimore (portions toll).

1. At Fort McHenry Tunnel, continue through right-hand tube.
2. Take the I-395 North exit (Exit Number 53) toward Downtown.
3. Take I-395 North toward Downtown/Inner Harbor.
4. Road divides, take left fork.
5. I-395 becomes South Howard Street. You will pass Camden Yards, on left.
6. Turn right onto West Pratt Street.
7. Continue past Baltimore Convention Center and Harborplace, both on right.
8. National Aquarium in Baltimore is on right, shortly before the ESPN Zone.
9. Buses and cars dropping off handicapped visitors may pull into Gunther Circle, on right. All others continue toward parking.

From points north via I-83: Pennsylvania, northern Maryland, and elsewhere

1. Follow I-83 South toward Baltimore until expressway ends in Baltimore City.
2. Turn right onto Lombard Street and stay in the left lane.
3. Turn left at Commerce Street.
4. Turn left at Pratt Street. The Aquarium is one block on the right, shortly before the ESPN Zone.
5. Buses and cars dropping off handicapped visitors may pull into Gunther Circle, on right. All others continue toward parking.

From points south via I-95: Washington, D.C., Virginia, and elsewhere

1. Follow I-95 North toward Baltimore
2. Take the I-395 North exit (Exit Number 53) toward Downtown.
3. Take I-395 North toward Downtown/Inner Harbor.
4. Road divides, take left fork.
5. I-395 becomes South Howard Street. You will pass Camden Yards, on left.
6. Turn right onto West Pratt Street.
7. Continue past Baltimore Convention Center and Harborplace, both on right.
8. National Aquarium in Baltimore is on right, shortly before the ESPN Zone.
9. Buses and cars dropping off handicapped visitors may pull into Gunther Circle, on right. All others continue toward parking.

From points west via I-70: Frederick, Hagerstown, and elsewhere

1. Follow I-70 East
2. Exit to I-695 South (toward I-95/Glen Burnie).
3. Exit to I-95 North towards Baltimore.
4. Follow I-95 North toward Baltimore
5. Take the I-395 North exit (Exit Number 53) toward Downtown.
6. Take I-395 North toward Downtown/Inner Harbor.
7. Road divides, take left fork.
8. I-395 becomes South Howard Street. You will pass Camden Yards, on left.
9. Turn right onto West Pratt Street.
10. Continue past Baltimore Convention Center and Harborplace, both on right.
11. National Aquarium in Baltimore is on right, shortly before the ESPN Zone.
12. Buses and cars dropping off handicapped visitors may pull into Gunther Circle, on right. All others continue toward parking.