The museum is located on the banks of the historic Susquehanna Flats in Havre de Grace, Md.
From north or south on I-95: Exit I-95 at exit 89 East to Havre de Grace. Proceed 4.6 miles, and turn right onto Juniata Street. Drive 1 mile to Revolution Street, and turn left. At Union Avenue, turn right. Proceed to the end of Union Avenue, and turn left onto Commerce Street. Follow signs to the museum.
From Eastern Shore points: Take MD Route 213 North to Route 40 East. Cross Hatem Bridge, and follow Route 40 to Revolution Street. Turn left onto Revolution Street. At Union Avenue, turn right. Proceed to the end of Union Avenue, and turn left onto Commerce Street. Follow signs to the museum.
From Pennsylvania: Take PA Route 272/MD Route 222 to Perryville. Cross Hatem Bridge, and follow MD Route 40 to Revolution Street. Turn left onto Revolution Street. At Union Avenue, turn right. Proceed to the end of Union Avenue, and turn left onto Commerce Street. Follow signs to the museum.